Results
| PMID | 21481374 |
| Gene Name | CSF1 |
| Condition | Endometriosis |
| Association |
Associated |
| Sex | Female |
| Associated genes | CSF-1 |
| Other associated phenotypes |
Endometriosis |
|
Fertil Steril. 2011 Jun 30;95(8):2464-6. doi: 10.1016/j.fertnstert.2011.03.026. Aligeti, Sabitha| Kirma, Nameer B| Binkley, Peter A| Schenken, Robert S| Tekmal, Rajeshwar Rao Department of Obstetrics and Gynecology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA. Although macrophage colony-stimulating factor (CSF-1) has been suggested to play a role in maintaining the chronic inflammatory response in endometriosis, our data suggest that CSF-1 may also play a role in early endometriosis lesion formation. We have shown that CSF-1, in an autocrine fashion, has a direct effect on endometrial epithelial cell proliferation and attachment to peritoneal mesothelial cells, early steps in endometriosis lesion formation on the peritoneum. Mesh Terms: Analysis of Variance| Autocrine Communication| Cell Adhesion| Cell Line| *Cell Movement| *Cell Proliferation| Coculture Techniques| Endometriosis/*metabolism/pathology| Endometrium/*metabolism/pathology| Epithelial Cells/*metabolism/pathology| F |
|